Name
Designations
Role
GMC number
My current role
I am a Consultant Renal Physician and Director of Research at CUH.
I am also Director of Research for Cambridge University Health Partners, Regional Specialty Advisor in Renal Medicine, Royal College of Physicians, Chief Investigator of the NIHR BioResource, Director of Gut Reaction, the Health Data Research UK Data Research Hub, and co-Director of the Cambridge-Yale translational research collaboration. I am the Editor in Chief of the British Journal of Renal Medicine. I Chair the Medical Advisory Committee of the Evelyn Trust.
I am honorary Professor of Experimental Medicine at the University of Cambridge and Director of Studies in Medicine at Trinity Hall, University of Cambridge. I have written five textbooks on pre-clinical and clinical medicine.
As an Emeritus NIHR Senior Investigator I lead a research programme in vascular biology, with a focus on TNF signalling in the microvasculature.
Previous history
I completed my undergraduate medical training at Nottingham University and trained in renal medicine in Cambridge, before completing research fellowships at Harvard, Yale and Cambridge Universities.
Publications
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Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies
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Longitudinal analysis reveals that delayed bystander CD8+ T cell activation and early immune pathology distinguish severe COVID-19 from mild disease
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Whole-genome sequencing of patients with rare diseases in a national health system
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Signaling through tumor necrosis receptor 2 induces stem cell marker in CD133+ regenerating tubular epithelial cells in acute cell-mediated rejection of human renal allografts.
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Tumor necrosis factor receptor-2 signaling pathways promote survival of cancer stem-like CD133+ cells in clear cell renal carcinoma.