Name
Designations
Role
GMC number
The good physician treats the disease; the great physician treats the patient who has the disease.
William Osler
My current role
I am a Consultant Paediatric Oncologist and Clinical Trialist, treating children with a range of childhood malignancies, with a special interest in Leukaemia and Neuroblastoma.
I am the National Institute of Health Research, Clinical Research Network (NIHR CRN) lead for paediatric oncology for the East of England; paediatric lead of the Cambridge Experimental Cancer Medicines Centre (ECMC); and Cambridge lead for the Innovative Therapies for Children with Cancer (ITCC) consortium.
I also lead a number of clinical trials locally and nationally, and represent Cambridge on national panels including the Novel Agents Group, Leukaemia Sub Group and Neuroblastoma Special Interest Group. These groups are responsible for clinical trials and improving treatments for childhood cancer in these special interest areas. I am also a member of the national VIVO Biobank Sample and Data Access committee that regulates access to this precious national resource.
Academically, I lead a number of translational research projects including a novel combination to induce differentiation in neuroblastoma and expediting whole genome sequencing results for childhood cancer, amongst others.
I am the lead examiner for paediatric clinical examinations for the University of Cambridge, School of Clinical Medicine.
Previous history
I completed my clinical training in paediatric haematology / oncology and haematopoietic stem cell transplant in Australia (Sydney Children's Hospital) and London (Royal Marsden Hospital).
I completed a clinical fellowship in early phase clinical trials and drug development; a Masters in clinical trials and epidemiology (University of Sydney) and PhD in leukaemia stem cell biology (University of Cambridge) as a Gates Cambridge scholar.
Membership and accreditations
- Fellow of Royal College of Paediatrics and Child Health
- Fellow of Royal Australasian College of Physicians
- Children’s Cancer and Leukaemia Group
- Novel Agents Group
- Childhood Leukaemia Clinician’s Network
- National Leukaemia Subgroup
- National Neuroblastoma Special Interest Group
- VIVO Biobank Sample and Data Access Committee
- Myechild2 trial steering committee
Personal interests
I enjoy nurturing my children and enjoying their laughs. I love to travel to all corners of the world, learning diversity of cultures; and swimming laps of the pool.
Publications
-
Preleukemic clonal evolution revealed using single-cell DNA sequencing and computational modelling
-
Blinatumomab for First-Line Treatment of Children and Young Persons With B-ALL
-
Managing febrile neutropenia in the UK in 2020
-
An infant with ETV6-NTRK3 fusion-positive congenital infantile fibrosarcoma and delayed response to conventional chemotherapy avoiding the need for TRK inhibition
-
Sphingolipid Modulation Activates Proteostasis Programs to Govern Human Hematopoietic Stem Cell Self-Renewal